Description

4-Bromo-2-(tert-Butyl)-6-Iodooxazolo[4,5-C]Pyridine is a high-value, multi-halogenated oxazolopyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its complex heterocyclic structure, featuring bromine and iodine substituents, makes it an indispensable building block for constructing novel molecular architectures with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials. The CAS number for this compound is 1305325-02-3.

Application

This specialized intermediate is designed for high-end research and development applications where precise molecular modification is required.

• Pharmaceutical Research: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Development: Used in creating advanced intermediates for new generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or charge-transport materials, due to its halogenated, electron-deficient core.
• Chemical Biology: Employed as a probe or labeling agent in bioconjugation chemistry, leveraging the reactivity of the halogen atoms for cross-coupling reactions.
• Catalyst & Ligand Synthesis: Acts as a starting material for the preparation of sophisticated nitrogen-containing ligands used in transition metal catalysis.
• Academic & Contract Research: Essential for methodological studies in organic synthesis, particularly in cross-coupling (e.g., Suzuki, Sonogashira) and heterocycle functionalization reactions.

Basic Information

Product Name	4-Bromo-2-(tert-Butyl)-6-Iodooxazolo[4,5-C]Pyridine
CAS No.	1305325-02-3
Molecular Formula	C₁₀H₁₀BrIN₂O
Molecular Weight	392.01 g/mol
Synonyms	4-Bromo-2-tert-butyl-6-iodo[1,3]oxazolo[4,5-c]pyridine; 2-(tert-Butyl)-4-bromo-6-iodooxazolo[4,5-c]pyridine; Oxazolo[4,5-c]pyridine, 4-bromo-2-(1,1-dimethylethyl)-6-iodo-; 4-Bromo-2-(1,1-dimethylethyl)-6-iodo-oxazolo[4,5-c]pyridine; 1305325-02-3; BTOIP; Multi-halogenated oxazolopyridine intermediate.
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-(tert-Butyl)-6-Iodooxazolo[4,5-C]Pyridine is synthesized and purified under controlled conditions to ensure the highest standards of chemical integrity and lot-to-lot consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profile as confirmed by advanced analytical techniques including HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent any potential degradation. Handle and store in accordance with all applicable laboratory safety regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.