Description

5-Chloro-3-(Dimethoxymethyl)-4-Iodo-2-Methoxypyridine is a high-value, multi-functional halogenated pyridine derivative designed for advanced synthetic chemistry. This compound serves as a critical versatile building block in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs), ligands, and functional materials where precise halogen and methoxy substitution patterns are required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a building block for creating specialized ligands in catalysis and functional organic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags due to its reactive iodine handle for further functionalization.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in custom synthesis projects and scale-up campaigns.

Basic Information

Item	Detail
Product Name	5-Chloro-3-(Dimethoxymethyl)-4-Iodo-2-Methoxypyridine
CAS No.	1305324-67-7
Molecular Formula	C9H11ClINO3
Molecular Weight	343.55 g/mol
Synonyms	5-Chloro-4-iodo-3-(dimethoxymethyl)-2-methoxypyridine; 2-Methoxy-5-chloro-3-(dimethoxymethyl)-4-iodopyridine; 4-Iodo-5-chloro-3-(dimethoxymethyl)-2-methoxypyridine; CAS 1305324-67-7
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-3-(Dimethoxymethyl)-4-Iodo-2-Methoxypyridine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure consistent purity and identity, critical for sensitive R&D and scale-up processes. Certificates of Analysis (COA) detailing purity (typically by HPLC/NMR), identity confirmation, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.