Description

4-Bromo-2-(tert-Butyl)-7-(Trimethylsilyl)-Oxazolo[4,5-C]Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is engineered to provide a unique combination of steric bulk and reactive handles, enabling the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, ligand synthesis, and material science research.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Research: Serves as a versatile precursor for synthesizing new crop protection agents and herbicides with enhanced properties.
• Ligand Synthesis: Used in the preparation of sophisticated ligands for catalysis, including those for cross-coupling and C-H activation reactions.
• Material Science: A building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its fused heterocyclic core.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.
• Academic & Industrial R&D: A critical reagent for method development and exploring new chemical spaces in synthetic organic chemistry.

Basic Information

Product Name	4-Bromo-2-(tert-Butyl)-7-(Trimethylsilyl)-Oxazolo[4,5-C]Pyridine
CAS No.	1305324-62-2
Molecular Formula	C15H23BrN2OSi
Molecular Weight	367.35 g/mol
Synonyms	4-Bromo-2-tert-butyl-7-(trimethylsilyl)oxazolo[4,5-c]pyridine; 2-(tert-Butyl)-4-bromo-7-(trimethylsilyl)oxazolo[4,5-c]pyridine; 7-(Trimethylsilyl)-2-tert-butyl-4-bromooxazolo[4,5-c]pyridine; Oxazolo[4,5-c]pyridine, 4-bromo-2-(1,1-dimethylethyl)-7-(trimethylsilyl)-; 1305324-62-2; TMS-Oxazolopyridine Bromide Derivative
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-(tert-Butyl)-7-(Trimethylsilyl)-Oxazolo[4,5-C]Pyridine is produced and tested under strict quality management systems to ensure batch-to-batch consistency and reliability for your critical research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.