Description

Dimethyl 1-Allyl-5,5-Difluorocyclohexane-1,3-Dicarboxylate is a high-value, multi-functional fluorinated building block and synthetic intermediate. Its molecular architecture, featuring a difluorocyclohexane core, an allyl group, and two ester functionalities, makes it a versatile precursor for advanced organic synthesis. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated cyclohexane scaffold to modulate bioavailability, metabolic stability, and receptor binding.
• Agrochemical Research: Used in developing new generation herbicides, fungicides, and insecticides where the introduction of fluorine atoms can enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and coatings with unique chemical resistance or surface properties.
• Ligand and Catalyst Synthesis: The allyl and ester groups provide handles for further functionalization to create chiral ligands or organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Research: An important substrate for studying the reactivity and conformational effects of gem-difluorocyclohexane units in organic molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific fluorinated intermediate.

Basic Information

Product Name	Dimethyl 1-Allyl-5,5-Difluorocyclohexane-1,3-Dicarboxylate
CAS No.	1296114-58-3
Molecular Formula	C13H18F2O4
Molecular Weight	276.28 g/mol
Synonyms	1-Allyl-5,5-difluorocyclohexane-1,3-dicarboxylic acid dimethyl ester; Dimethyl 1-allyl-5,5-difluorocyclohexane-1,3-dicarboxylate; 5,5-Difluoro-1-(2-propen-1-yl)cyclohexane-1,3-dicarboxylic Acid Dimethyl Ester; Allyl Difluorocyclohexanedicarboxylate Dimethyl Ester
EINECS	Contact for details

Quality Control

Our Dimethyl 1-Allyl-5,5-Difluorocyclohexane-1,3-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.