Description

(8α,9S)- 9-Isothiocyanato-6'-Methoxy-Cinchonan CAS NO 1295509-64-6 is a high-purity, specialized cinchona alkaloid derivative characterized by its unique isothiocyanate functional group. This compound is a critical advanced pharmaceutical intermediate and a valuable chiral building block for the synthesis of complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing new active ingredients and catalysts.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel therapeutic agents, particularly in anti-malarial and anti-arrhythmic drug research.
• Asymmetric Catalysis: Serves as a ligand or catalyst precursor in stereoselective synthesis, enabling the production of enantiomerically pure compounds.
• Chemical Research & Development: Used as a reference standard and building block in medicinal chemistry and process development for new chemical entities.
• Agrochemical Synthesis: Intermediate in the development of advanced, chiral pesticides and herbicides.
• Academic Research: Valuable tool for studying alkaloid chemistry, reaction mechanisms, and developing new synthetic methodologies.

Basic Information

Item	Detail
Product Name	(8α,9S)- 9-Isothiocyanato-6'-Methoxy-Cinchonan
CAS No.	1295509-64-6
Molecular Formula	C₂₁H₂₃N₃O₂S
Molecular Weight	381.49 g/mol
Synonyms	9-Isothiocyanato-6'-methoxycinchonan; (8α,9S)-Cinchonan-9-yl isothiocyanate, 6'-methoxy-; 6'-Methoxycinchonan-9-yl isothiocyanate; (9S)-9-Isothiocyanato-6'-methoxycinchonan; Cinchona alkaloid isothiocyanate derivative; 9-ITC-6'-OMe-Cinchonan
EINECS	Contact for details

Quality Control

Every batch of (8α,9S)- 9-Isothiocyanato-6'-Methoxy-Cinchonan is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity intermediates. Comprehensive analysis includes identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.