Description

Bocnh-Peg6-Ch2Ch2N3 is a heterobifunctional polyethylene glycol (PEG) crosslinker featuring a tert-butyloxycarbonyl (Boc) protected amine at one terminus and an azide group at the other. This compound is essential for creating stable, cleavable linkages in bioconjugation and materials science, enabling the controlled assembly of biomolecules and polymers. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, proteomics, and advanced polymer synthesis.

Application

• Bioconjugation and ADC Development: Used as a spacer/linker for attaching cytotoxic drugs to antibodies or proteins in Antibody-Drug Conjugate (ADC) research and production.
• Peptide and Protein Modification: Facilitates site-specific PEGylation to improve the pharmacokinetic properties, solubility, and stability of therapeutic peptides and proteins.
• Click Chemistry: The terminal azide group enables efficient, bioorthogonal Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for labeling and crosslinking biomolecules.
• Polymer and Hydrogel Synthesis: Serves as a functional building block for creating smart, responsive hydrogels and functionalized polymers for drug delivery systems.
• Surface Functionalization: Used to modify surfaces (e.g., nanoparticles, chips, beads) with amine-reactive groups for subsequent biomolecule immobilization.
• Diagnostic Reagent Preparation: Employed in the synthesis of reagents for diagnostic assays, including fluorescence labeling and probe construction.

Basic Information

Product Name	Bocnh-Peg6-Ch2Ch2N3
CAS No.	1292268-15-5
Molecular Formula	C30H58N4O13
Molecular Weight	682.8 g/mol
Synonyms	Boc-NH-PEG6-azide; Boc-Amine-PEG6-N3; 2-[2-[2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl (2-{[(tert-butoxy)carbonyl]amino}ethyl)carbamate; tert-Butyl N-[2-({2-[2-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethyl)carbamoylamino]ethylcarbamate; Azido-PEG6-Boc-amine; Boc-N-amido-PEG6-azide; Boc-protected amino-PEG6-azide
EINECS	Contact for details

Quality Control

Our Bocnh-Peg6-Ch2Ch2N3 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under inert atmosphere for long-term stability. The product is hygroscopic and should be kept in a dry environment. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.