Description

C-[1-(1-Pyridin-2-Yl-Ethyl)-Piperidin-2-Yl]-Methylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a complex piperidine-pyridine hybrid structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material to develop next-generation therapeutic candidates with high specificity and potency.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug molecules, especially for neurological and psychiatric disorders.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new pharmacologically active compounds.
• Ligand Synthesis: Acts as a key component for creating selective ligands targeting specific neurotransmitter receptors (e.g., serotonin, dopamine receptors).
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for API manufacturing under GMP conditions.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis: A starting point for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	C-[1-(1-Pyridin-2-Yl-Ethyl)-Piperidin-2-Yl]-Methylamine Hydrochloride
CAS No.	1289384-75-3
Molecular Formula	C14H23N3·HCl
Molecular Weight	269.81 g/mol (Free base: 233.35 g/mol)
Synonyms	1-(1-(Pyridin-2-yl)ethyl)piperidin-2-yl)methanamine hydrochloride; (1-(1-(Pyridin-2-yl)ethyl)piperidin-2-yl)methanamine HCl; 2-Piperidinemethanamine, 1-[1-(2-pyridinyl)ethyl]-, hydrochloride; C-[1-(1-Pyridin-2-yl-ethyl)-piperidin-2-yl]-methylamine hydrochloride; (R/S)-C-[1-(1-Pyridin-2-yl-ethyl)-piperidin-2-yl]-methylamine hydrochloride; CAS 1289384-75-3
EINECS	Contact for details

Quality Control

Our C-[1-(1-Pyridin-2-Yl-Ethyl)-Piperidin-2-Yl]-Methylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure compliance with stringent specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.