Description

5-Fluoro-2-Isopropoxyisonicotinaldehyde is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an aldehyde and a fluoro-substituted isopropoxy group, makes it indispensable for constructing complex molecular architectures. This compound is primarily utilized by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including kinase inhibitors and other biologically relevant heterocycles.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for targeted cancer therapies and kinase inhibitors.
• Agrochemical Research: Building block for developing new generation herbicides and fungicides with enhanced efficacy and selectivity.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Enables the creation of fluorinated probes for studying enzyme mechanisms and biological pathways.
• Advanced Material Development: Serves as a monomer or functionalizing agent for specialty polymers and electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name	5-Fluoro-2-Isopropoxyisonicotinaldehyde
CAS No.	1289027-23-1
Molecular Formula	C10H12FNO2
Molecular Weight	197.21 g/mol
Synonyms	5-Fluoro-2-(1-methylethoxy)-4-pyridinecarboxaldehyde; 4-Pyridinecarboxaldehyde, 5-fluoro-2-(1-methylethoxy)-; 5-Fluoro-2-isopropoxy-4-formylpyridine; 5-Fluoro-2-(isopropoxy)isonicotinaldehyde; 5-Fluoro-2-(propan-2-yloxy)isonicotinaldehyde; 2-Isopropoxy-5-fluoroisonicotinaldehyde; 5-Fluoro-2-isopropoxy-4-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-2-Isopropoxyisonicotinaldehyde is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as confirmed by HPLC, GC, NMR, and mass spectrometry. Our quality commitment ensures material consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.