Description

5-Amino-2-Bromoisonicotinaldehyde is a high-purity brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its dual functional groups, which enable selective modifications for constructing complex heterocyclic scaffolds. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Functional Material Development: Building block for organic electronic materials, such as those used in OLEDs and sensors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	5-Amino-2-Bromoisonicotinaldehyde
CAS No.	1289021-84-6
Molecular Formula	C6H5BrN2O
Molecular Weight	201.02 g/mol
Synonyms	2-Bromo-5-amino-4-pyridinecarboxaldehyde; 4-Pyridinecarboxaldehyde, 5-amino-2-bromo-; 5-Amino-2-bromopyridine-4-carbaldehyde; 2-Bromo-5-aminopyridine-4-carboxaldehyde; 5-Amino-2-bromo-4-formylpyridine; 4-Formyl-5-amino-2-bromopyridine; 2-Bromo-5-aminopyridine-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Bromoisonicotinaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality management system supports development under ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.