Description

(4-Aminopiperidin-1-Yl)(Pyridin-2-Yl)Methanone Dihydrochloride is a high-purity, pharmaceutically relevant chemical building block. This compound serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) and is valued for its role in medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and fine chemical manufacturers focused on drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Biology Probes: Serves as a precursor for developing tool compounds and probes to study biological pathways.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke APIs for clinical trials.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening.
• Academic Research: Used in university and institutional labs for fundamental research in organic and medicinal chemistry.

Basic Information

Product Name	(4-Aminopiperidin-1-Yl)(Pyridin-2-Yl)Methanone Dihydrochloride
CAS No.	1286274-40-5
Molecular Formula	C11H16Cl2N3O
Molecular Weight	278.17 g/mol
Synonyms	2-Pyridinyl(4-aminopiperidin-1-yl)methanone dihydrochloride; (4-Aminopiperidin-1-yl)(pyridin-2-yl)methanone hydrochloride; 1-(Pyridine-2-carbonyl)piperidin-4-amine dihydrochloride; (4-Amino-1-piperidinyl)(2-pyridinyl)methanone dihydrochloride; 4-Amino-1-(2-pyridinylcarbonyl)piperidine dihydrochloride; (4-Aminopiperidin-1-yl)(2-pyridyl)ketone dihydrochloride; 2-[(4-Aminopiperidin-1-yl)carbonyl]pyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our (4-Aminopiperidin-1-Yl)(Pyridin-2-Yl)Methanone Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.