Description

2-Bromo-4-Fluorophenyl Chlorothioformate is a specialized organosulfur reagent featuring a reactive chlorothioformate group on a halogenated aromatic ring. This compound matters as a versatile building block for introducing the 2-bromo-4-fluorophenylthio moiety into target molecules, enabling the synthesis of complex intermediates in advanced chemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated arylthio groups.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the specific halogen pattern influences bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers or additives for advanced polymers and functional materials.
• Chemical Biology Probes: Useful for modifying peptides, proteins, or other biomolecules to study biological pathways or for diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom chemical synthesis services catering to advanced R&D projects.

Basic Information

Product Name	2-Bromo-4-Fluorophenyl Chlorothioformate
CAS No.	1284227-56-0
Molecular Formula	C7H3BrClFOS
Molecular Weight	269.52 g/mol
Synonyms	Chlorocarbonothioic Acid O-(2-Bromo-4-fluorophenyl) Ester; 2-Bromo-4-fluorophenyl chloromethanethioate; Carbonochloridothioic Acid O-(2-Bromo-4-fluorophenyl) Ester; (2-Bromo-4-fluorophenoxy)(chloro)methanethione; O-(2-Bromo-4-fluorophenyl) Chlorothioformate
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Fluorophenyl Chlorothioformate is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its reactivity as a strong acid/organic solvent derivative and high volatility, ensure the container is kept tightly sealed and stored separately from bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.