Description

3-Bromo-5-(4-(Chloromethyl)Piperidin-1-Ylsulfonyl)Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is strategically important for its dual reactive sites—the bromo and chloromethyl groups—which enable selective derivatization and the construction of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly for kinase inhibitors and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, leveraging its sulfonyl piperidine scaffold for bioactivity.
• Chemical Biology Probe Synthesis: Serves as a versatile scaffold for creating molecular probes and tool compounds used in target identification and validation studies.
• Material Science: Employed in the research and development of specialty polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Bromo-5-(4-(Chloromethyl)Piperidin-1-Ylsulfonyl)Pyridine
CAS No.	1284117-78-7
Molecular Formula	C11H14BrClN2O2S
Molecular Weight	365.66 g/mol
Synonyms	3-Bromo-5-[(4-chloromethyl)piperidin-1-ylsulfonyl]pyridine; 1-(3-Bromopyridin-5-yl)sulfonyl-4-(chloromethyl)piperidine; 4-(Chloromethyl)-1-[(3-bromo-5-pyridinyl)sulfonyl]piperidine; 3-Bromo-5-(4-chloromethyl-piperidine-1-sulfonyl)-pyridine; 3-Bromo-5-(4-chloromethylpiperidine-1-sulfonyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-(4-(Chloromethyl)Piperidin-1-Ylsulfonyl)Pyridine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing all relevant specifications is provided with each shipment. We support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.