Description

3'-Azido-3'-Deoxy-5-Methylcytidine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel antiviral and anticancer agents, particularly in the development of nucleoside reverse transcriptase inhibitors. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on innovative therapeutic solutions. The structural modification at the 3'-position with an azido group provides unique biochemical properties essential for probing biological mechanisms and creating targeted drug candidates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of experimental antiviral and antiretroviral drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA/RNA synthesis and viral replication mechanisms.
• Antiviral Agent Development: Serves as a core scaffold for developing novel nucleoside analogs targeting viruses such as HIV and hepatitis.
• Oncology Research: Investigated for its potential incorporation into chemotherapeutic agents designed to disrupt cancer cell proliferation.
• Proteomics & Genomics: Employed in the study of nucleic acid metabolism and for labeling applications in molecular biology.
• Fine Chemical Synthesis: A valuable building block for custom synthesis and the production of specialized nucleotide libraries for high-throughput screening.

Basic Information

Product Name	3'-Azido-3'-Deoxy-5-Methylcytidine
CAS No.	1282040-14-5
Molecular Formula	C10H13N7O4
Molecular Weight	295.26 g/mol
Synonyms	3'-Azido-3'-deoxy-5-methylcytidine; 5-Methyl-3'-azido-3'-deoxycytidine; 3'-N3-5-Me-dC; 3'-Azido-5-methyl-2',3'-dideoxycytidine; Azidomethylcytidine derivative; 1-((2R,3S,5R)-3-Azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our 3'-Azido-3'-Deoxy-5-Methylcytidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets stringent research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data and impurity profiles are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.