Description

5-Chloro-2-Methoxy-3-(2,2,2-Trifluoroethoxy)Pyridine is a high-purity, multi-functional pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring chloro, methoxy, and trifluoroethoxy substituents, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production.

Basic Information

Product Name	5-Chloro-2-Methoxy-3-(2,2,2-Trifluoroethoxy)Pyridine
CAS No.	1280786-68-6
Molecular Formula	C8H7ClF3NO2
Molecular Weight	241.59 g/mol
Synonyms	3-(2,2,2-Trifluoroethoxy)-5-chloro-2-methoxypyridine; 5-Chloro-3-(2,2,2-trifluoroethoxy)-2-methoxypyridine; 2-Methoxy-5-chloro-3-(2,2,2-trifluoroethoxy)pyridine; Pyridine, 5-chloro-2-methoxy-3-(2,2,2-trifluoroethoxy)-; CAS 1280786-68-6
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2-Methoxy-3-(2,2,2-Trifluoroethoxy)Pyridine is produced under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to fluoride and strong alkali; ensure it is stored separately from such materials to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.