Description

4,8-Dichloro-1,7-Naphthyridine is a high-purity, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile precursor for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors or antimicrobial agents.
• Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, or insecticides with novel modes of action.
• Ligand & Catalyst Development: Used in the preparation of specialized nitrogen-containing ligands for catalytic systems in fine chemical synthesis.
• Material Science Precursor: Employed in the research of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes to study biological processes and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4,8-Dichloro-1,7-Naphthyridine
CAS No.	1279894-03-9
Molecular Formula	C8H4Cl2N2
Molecular Weight	199.04 g/mol
Synonyms	1,7-Naphthyridine, 4,8-dichloro-; 4,8-Dichloro-1,7-naphthyridine; 4,8-Dichloro-1,7-diazanaphthalene; 1,7-Diazanaphthalene, 4,8-dichloro-; Dichloro-1,7-naphthyridine; 4,8-Dichloro-1,7-naphthyridine (CAS 1279894-03-9)
EINECS	Contact for details

Quality Control

Our 4,8-Dichloro-1,7-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.