Description

6-Bromo-n-Cyclobutylnicotinamide (CAS NO 1276014-64-2) is a high-value brominated nicotinamide derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor research.
• Agrochemical Research: Used in the development of new herbicides and pesticides with novel modes of action.
• Chemical Biology Probe: Serves as a precursor for labeled compounds used in target identification and validation studies.
• Material Science: Employed in the synthesis of organic electronic materials and liquid crystals.
• Academic & Contract Research: Essential for method development and novel reaction pathway exploration in university and CRO laboratories.
• Custom Synthesis: Starting material for the tailored production of complex, bromine-substituted heterocyclic compounds.

Basic Information

Product Name	6-Bromo-n-Cyclobutylnicotinamide
CAS No.	1276014-64-2
Molecular Formula	C10H11BrN2O
Molecular Weight	255.11 g/mol
Synonyms	6-Bromo-N-cyclobutylnicotinamide; 6-Bromo-N-cyclobutyl-3-pyridinecarboxamide; Nicotinamide, 6-bromo-N-cyclobutyl-; 3-Pyridinecarboxamide, 6-bromo-N-cyclobutyl-; 6-Bromonicotinoyl cyclobutylamide; 6-Bromo-3-carbamoylpyridine, N-cyclobutyl derivative
EINECS	Contact for details

Quality Control

Our 6-Bromo-n-Cyclobutylnicotinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.