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N3-Peg7-Oh CAS NO 1274892-60-2


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CAS No.:1274892-60-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N3-Peg7-Oh is a heterobifunctional polyethylene glycol (PEG) linker featuring an azide (N3) group at one terminus and a hydroxyl (OH) group at the other. This compound is a critical building block in bioconjugation and click chemistry, enabling the precise, high-yield coupling of biomolecules and materials under mild, aqueous conditions. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-purity linkers for developing novel therapeutics, diagnostics, and functionalized surfaces.

Application

  • Bioconjugation reagent for attaching azide-modified molecules (e.g., drugs, dyes, peptides) to hydroxyl-presenting surfaces or polymers.
  • Key intermediate in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutic agents via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (CuAAC/SPAAC).
  • Functionalization of nanoparticles, liposomes, and hydrogels to introduce reactive handles for further chemical modification.
  • PEGylation of proteins and peptides to improve solubility, stability, and pharmacokinetic profiles.
  • Crosslinker in the development of biodegradable and stimuli-responsive polymer networks for drug delivery.
  • Surface modification of biosensors and diagnostic devices to create specific binding interfaces.
  • Tool compound in chemical biology for probing biological processes and constructing complex molecular architectures.

Basic Information

Product Name N3-Peg7-Oh
CAS No. 1274892-60-2
Molecular Formula C17H35N3O8
Molecular Weight 409.48 g/mol
Synonyms Azido-PEG7-alcohol; 1-Azido-3,6,9,12,15,18,21-heptaoxatricosan-23-ol; 17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-ol (PEG7 derivative); N3-PEG7-OH; Azidoheptaethylene glycol; Azido-PEG7-OH; Azido-PEG7-alcohol; Heterobifunctional PEG linker, N3-PEG7-OH
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Quality Control

Our N3-Peg7-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for sensitive bioconjugation applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere for long-term stability. The product is hygroscopic and light-sensitive; allow the vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item Specification
Appearance Colorless to pale yellow viscous liquid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Molecular Weight Confirmation (MS) Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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