Description

n-(tert-Butyl)-5-Cyanopyridine-3-Sulfonamide is a high-purity, advanced pharmaceutical intermediate characterized by its sulfonamide and cyano-substituted pyridine core. This compound is of significant commercial importance as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Serves as a building block for developing new pesticides and herbicides with specific modes of action.
• Chemical Synthesis: Used in organic synthesis for constructing complex heterocyclic compounds and functionalized pyridine derivatives.
• Material Science: Potential applications in the research and development of advanced organic materials and ligands for catalysis.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	n-(tert-Butyl)-5-Cyanopyridine-3-Sulfonamide
CAS No.	1272356-73-6
Molecular Formula	C10H13N3O2S
Molecular Weight	239.29 g/mol
Synonyms	5-Cyano-N-(tert-butyl)pyridine-3-sulfonamide; 3-Pyridinesulfonamide, 5-cyano-N-(1,1-dimethylethyl)-; N-tert-Butyl-5-cyanopyridine-3-sulfonamide; 5-Cyano-N-(tert-butyl)nicotinsulfonamid; 1272356-73-6; tert-Butyl 5-cyanopyridin-3-ylsulfonamide
EINECS	Contact for details

Quality Control

Our n-(tert-Butyl)-5-Cyanopyridine-3-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.