Description

5-(2-Pyrrolidinyl)-3-Pyridinecarbonitrile is a high-purity, advanced pharmaceutical intermediate featuring a unique pyrrolidine-pyridine hybrid scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents, kinase inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening (HTS) for drug discovery programs.
• CNS Drug Development: Serves as a precursor in the synthesis of potential therapeutics targeting neurological disorders.
• Kinase Inhibitor Synthesis: Employed in the construction of heterocyclic cores for potential kinase inhibitor candidates in oncology research.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways.
• Agrochemical Research: Acts as an intermediate in the discovery of new crop protection agents and pesticides.

Basic Information

Product Name	5-(2-Pyrrolidinyl)-3-Pyridinecarbonitrile
CAS No.	1270380-93-2
Molecular Formula	C10H11N3
Molecular Weight	173.22 g/mol
Synonyms	3-Cyano-5-(pyrrolidin-2-yl)pyridine; 5-(Pyrrolidin-2-yl)nicotinonitrile; 2-(5-Cyanopyridin-3-yl)pyrrolidine; 5-(2-Pyrrolidinyl)-3-cyanopyridine; 3-Pyridinecarbonitrile, 5-(2-pyrrolidinyl)-; Pyrrolidine, 2-(5-cyano-3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 5-(2-Pyrrolidinyl)-3-Pyridinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all specified parameters. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.