Description

(2-Chloro-Pyridin-3-Yl)-Piperazin-1-Yl-Methanone Hydrochloride is a high-purity chemical building block and pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop novel bioactive molecules.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced crop protection agents and pesticides.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for chemical methodology development and biological screening.

Basic Information

Product Name	(2-Chloro-Pyridin-3-Yl)-Piperazin-1-Yl-Methanone Hydrochloride
CAS No.	1270138-42-5
Molecular Formula	C11H13Cl2N3O
Molecular Weight	274.15 g/mol
Synonyms	1-[(2-Chloropyridin-3-yl)carbonyl]piperazine hydrochloride; (2-Chloro-3-pyridinyl)(piperazin-1-yl)methanone hydrochloride; 2-Chloro-N-(piperazin-1-yl)nicotinamide hydrochloride; 3-(Piperazine-1-carbonyl)-2-chloropyridine hydrochloride; 2-Chloro-3-piperazinecarbonylpyridine hydrochloride; 1-(2-Chloronicotinoyl)piperazine hydrochloride; (2-Chloro-3-pyridyl)(piperazin-1-yl)methanone HCl
EINECS	Contact for details

Quality Control

Our (2-Chloro-Pyridin-3-Yl)-Piperazin-1-Yl-Methanone Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.