Description

1-(2,4-Bis(Trifluoromethyl)Phenyl)Ethan-1-Ol CAS NO 1265177-56-7 is a high-value fluorinated aromatic alcohol, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring two electron-withdrawing trifluoromethyl groups, makes it indispensable for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Fluorinated component used in the synthesis of advanced electronic materials for displays and lighting, improving thermal stability and optical properties.
• Catalyst & Ligand Development: Precursor for creating specialized ligands in asymmetric catalysis, enabling more efficient and selective chemical transformations.
• Polymer & Specialty Chemicals: Monomer or modifier for engineering plastics and high-performance polymers, imparting oil, water, and chemical resistance.
• Academic & Contract Research: Essential reference standard and starting material for methodological development in organic and medicinal chemistry research.

Basic Information

Product Name	1-(2,4-Bis(Trifluoromethyl)Phenyl)Ethan-1-Ol
CAS No.	1265177-56-7
Molecular Formula	C10H6F6O
Molecular Weight	256.15 g/mol
Synonyms	1-[2,4-Bis(trifluoromethyl)phenyl]ethanol; α-Methyl-2,4-bis(trifluoromethyl)benzenemethanol; 2,4-Bis(trifluoromethyl)phenyl methyl carbinol; (2,4-Bis(trifluoromethyl)phenyl)ethanol; 1-(2,4-Bis(trifluoromethyl)phenyl)ethanol; 2,4-Bis(CF3)C6H3CH(OH)CH3
EINECS	Contact for details

Quality Control

Every batch of 1-(2,4-Bis(Trifluoromethyl)Phenyl)Ethan-1-Ol is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to moisture and oxidation; consider storage under an inert atmosphere for long-term preservation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Purity (Chiral HPLC)	Contact for details (Enantiomeric excess)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.