Description

o-(Pentafluorobenzyloxycarbonyl)Benzoyl Chloride is a specialized, high-purity benzoyl chloride derivative featuring a pentafluorobenzyloxycarbonyl protecting group. This compound matters as a critical building block in advanced organic synthesis, enabling the precise introduction of protected carboxylic acid functionalities under mild conditions. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, as well as by fine chemical manufacturers producing complex intermediates for life science applications.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of peptide mimetics and other bioactive molecules requiring orthogonal protection strategies.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides where the pentafluorobenzyl group can influence bioavailability and stability.
• Protecting Group Chemistry: Serves as an effective reagent for introducing the pentafluorobenzyloxycarbonyl (Pfb) protecting group for carboxylic acids, which can be selectively removed under specific conditions.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and molecular recognition studies.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with unique fluorinated properties.
• Diagnostic Reagent Manufacturing: Used in the production of labeling agents and probes for analytical and diagnostic applications.

Basic Information

Product Name	o-(Pentafluorobenzyloxycarbonyl)Benzoyl Chloride
CAS No.	1262207-98-6
Molecular Formula	C₁₅H₆ClF₅O₃
Molecular Weight	388.65 g/mol
Synonyms	2-[(Pentafluorobenzyloxy)carbonyl]benzoyl chloride; o-[(Pentafluorobenzyloxy)carbonyl]benzoyl chloride; Benzoyl chloride, 2-[(2,3,4,5,6-pentafluorobenzyloxy)carbonyl]-; Pentafluorobenzyl 2-(chlorocarbonyl)benzoate; Pfb-protected benzoyl chloride; 2-(Pentafluorobenzyloxycarbonyl)benzoyl chloride
EINECS	Contact for details

Quality Control

Our o-(Pentafluorobenzyloxycarbonyl)Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.