Description

(3-Fluoro-2-Iodophenyl)Methanol is a versatile fluorinated and iodinated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents on the aromatic ring, makes it a highly valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially for fluorinated active pharmaceutical ingredients (APIs) targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for synthesizing functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	(3-Fluoro-2-Iodophenyl)Methanol
CAS No.	1261827-82-0
Molecular Formula	C7H6FIO
Molecular Weight	252.03 g/mol
Synonyms	(3-Fluoro-2-iodophenyl)methanol; 2-Iodo-3-fluorobenzyl alcohol; (3-Fluoro-2-iodobenzyl) alcohol; 1-(Hydroxymethyl)-3-fluoro-2-iodobenzene; 3-Fluoro-2-iodobenzyl alcohol; Benzenemethanol, 3-fluoro-2-iodo-; 1261827-82-0
EINECS	Contact for details

Quality Control

Our (3-Fluoro-2-Iodophenyl)Methanol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements. Specifications can be customized to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The compound is light-sensitive; prolonged exposure should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.