Description

1H-Pyrrolo[2,3-B]Pyridine-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound is critical for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for its role as a key building block.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic core structure.
• Material Science: Serves as a precursor for creating functionalized organic materials and ligands for catalysis.
• Chemical Synthesis: Acts as a versatile acylating agent in multi-step synthetic routes for complex heterocyclic compounds.
• Bioconjugation: Potential use in modifying biomolecules due to its reactive carbonyl chloride functional group.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-4-Carbonyl Chloride
CAS No.	1261784-70-6
Molecular Formula	C9H5ClN2O
Molecular Weight	192.60 g/mol
Synonyms	4-Pyrrolo[2,3-b]pyridinecarbonyl chloride; 1H-Pyrrolo[2,3-b]pyridine-4-carbonyl chloride; 4-(Chlorocarbonyl)-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole-4-carbonyl chloride; 4-Carboxy-7-azaindole chloride; 1H-Pyrrolo[2,3-b]pyridine-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.