Description

2-Amino-4-Methoxybenzoyl Chloride is a versatile and highly reactive aromatic acyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 2-amino-4-methoxybenzoyl moiety, enabling the construction of complex molecular architectures with specific functional properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific benzamide or anilide structures.
• Dye and Pigment Manufacturing: Acts as a core component for synthesizing high-performance azo dyes and organic pigments with enhanced lightfastness and color properties.
• Polymer Chemistry: Employed as a monomer or cross-linking agent for creating specialty polyamides, polyimides, and other high-performance polymers.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials, host materials, and other functional components in display and lighting technologies.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Amino-4-Methoxybenzoyl Chloride
CAS No.	1261775-20-5
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	4-Methoxy-2-aminobenzoyl chloride; 2-Amino-4-methoxybenzoic acid chloride; 2-Amino-p-anisoyl chloride; 4-Methoxyanthraniloyl chloride; (2-Amino-4-methoxyphenyl)methanone chloride; 2-Carbamoyl-5-methoxyphenyl chloride; Benzoic acid, 2-amino-4-methoxy-, chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-Methoxybenzoyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.