Description

5-(2,3-Difluorophenyl)Pyridine-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate featuring a difluorophenyl-substituted pyridine core. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the biological activity of the difluorophenyl and nitrile groups.
• Material Science: Serves as a monomer or ligand in the creation of specialized polymers and metal-organic frameworks (MOFs).
• Organic Synthesis Building Block: Employed in cross-coupling reactions and cyanation chemistry to construct more complex heterocyclic systems.
• Life Science Reagents: Utilized in biochemical research as a probe or inhibitor scaffold for studying enzyme function.

Basic Information

Product Name	5-(2,3-Difluorophenyl)Pyridine-3-Carbonitrile
CAS No.	1261732-07-3
Molecular Formula	C12H6F2N2
Molecular Weight	216.19 g/mol
Synonyms	3-Cyano-5-(2,3-difluorophenyl)pyridine; 5-(2,3-Difluorophenyl)-3-pyridinecarbonitrile; 2,3-Difluoro-5-(3-cyanopyridin-5-yl)benzene; 5-(2,3-Difluorophenyl)nicotinonitrile; Pyridine, 5-(2,3-difluorophenyl)-3-cyano-; CAS 1261732-07-3
EINECS	Contact for details

Quality Control

Our 5-(2,3-Difluorophenyl)Pyridine-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.