Description

2-Fluoro-3-Hydroxybenzoyl Chloride is a specialized aromatic acid chloride derivative that serves as a critical building block in advanced organic synthesis. Its unique fluorinated and hydroxylated structure makes it a valuable precursor for introducing specific functional groups into target molecules with high precision. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and pesticides with enhanced activity and selectivity.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated aromatic cores for advanced electronic display and lighting materials.
• Polymer Modification: Monomer for introducing fluorine and phenol functionalities into specialty polymers to alter thermal and chemical resistance.
• Peptide & Protein Research: Acylating agent for modifying amino acids or creating custom fluorescent probes and tags.
• Chemical Research & Development: Versatile reagent for exploring new synthetic pathways and creating custom fluorinated compounds in academic and industrial R&D labs.

Basic Information

Product Name	2-Fluoro-3-Hydroxybenzoyl Chloride
CAS No.	1261621-20-8
Molecular Formula	C7H4ClFO2
Molecular Weight	174.56 g/mol
Synonyms	3-Hydroxy-2-fluorobenzoyl chloride; 2-Fluoro-3-hydroxybenzoic acid chloride; 2-Fluoro-3-hydroxybenzoyl chloride; 2-Fluoro-3-hydroxy-benzoic acid chloride; 2-Fluoro-3-hydroxybenzoic acid, acid chloride; (2-Fluoro-3-hydroxyphenyl)carbonyl chloride; 2-Fluoro-3-hydroxybenzoylchloride; 1261621-20-8
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Hydroxybenzoyl Chloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.