Description

6-Chloro-2-Iodo-3-Methylpyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialized polymers and liquid crystals.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Ligand Synthesis: Used to prepare novel nitrogen-containing ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	6-Chloro-2-Iodo-3-Methylpyridine
CAS No.	1261473-80-6
Molecular Formula	C6H5ClIN
Molecular Weight	253.47 g/mol
Synonyms	2-Iodo-6-chloro-3-methylpyridine; 3-Methyl-2-iodo-6-chloropyridine; 6-Chloro-3-methyl-2-iodopyridine; 2-Iodo-6-chloro-3-picoline; 6-Chloro-2-iodo-3-picoline; 2,6-Dihalogenated-3-methylpyridine; 6-Chloro-2-iodo-3-methylpyridine (CAS 1261473-80-6)
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Iodo-3-Methylpyridine is manufactured under strict quality management systems. We provide material with typical purity levels exceeding 97% (by HPLC), tailored to meet the rigorous demands of research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch. Our quality commitment ensures consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.