Description

1-(6-Iodo-7-Methyl-2,3-Dihydro-1H-Pyrido[2,3-B]-[1,4]Oxazin-1-Yl)-2,2-Dimethylpropan-1-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for complex small molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in high-throughput screening.
• Process Chemistry Development: Serves as a critical intermediate for scaling up and optimizing synthetic routes for potential APIs under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic methodologies and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	1-(6-Iodo-7-Methyl-2,3-Dihydro-1H-Pyrido[2,3-B]-[1,4]Oxazin-1-Yl)-2,2-Dimethylpropan-1-One
CAS No.	1261365-43-8
Molecular Formula	C14H17IN2O2
Molecular Weight	372.20 g/mol
Synonyms	1-(6-Iodo-7-methyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-1-yl)-2,2-dimethylpropan-1-one; 2,2-Dimethyl-1-(6-iodo-7-methyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-1-yl)propan-1-one; 6-Iodo-7-methyl-1-(2,2-dimethylpropanoyl)-1,2,3,4-tetrahydropyrido[2,3-b][1,4]oxazine; Iodo-methyl-dihydro-pyrido-oxazine propanone derivative
EINECS	Contact for details

Quality Control

Our 1-(6-Iodo-7-Methyl-2,3-Dihydro-1H-Pyrido[2,3-B]-[1,4]Oxazin-1-Yl)-2,2-Dimethylpropan-1-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch to document compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.