Description

3,5-Dichloro-6-Fluoropyridin-2-Amine is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its value lies in its unique halogenated structure, which provides versatile reactivity for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of advanced organic materials, including liquid crystals, organic semiconductors, and functional polymers.
• Chemical Biology Probes: Employed as a scaffold for creating molecular probes and diagnostic agents due to its modifiable amine and halogen groups.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex biaryl and heteroaryl structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	3,5-Dichloro-6-Fluoropyridin-2-Amine
CAS No.	1261269-88-8
Molecular Formula	C5H3Cl2FN2
Molecular Weight	180.99 g/mol
Synonyms	2-Amino-3,5-dichloro-6-fluoropyridine; 6-Fluoro-3,5-dichloropyridin-2-amine; 3,5-Dichloro-6-fluoro-2-pyridinamine; 2-Pyridinamine, 3,5-dichloro-6-fluoro-; 3,5-Dichloro-6-fluoro-2-aminopyridine; 6-Fluoro-3,5-dichloro-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-6-Fluoropyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.