Description

3-Fluoro-4-(Piperidin-4-Yl)Pyridine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a distinct fluorinated pyridine-piperidine scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted small molecule therapeutics. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel drug candidates for oncology, CNS disorders, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other biologically active molecules.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology: Serves as a versatile scaffold for the development of chemical probes and tool compounds.
• API Development: Employed in the research-scale preparation of active pharmaceutical ingredients (APIs) during preclinical development.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	3-Fluoro-4-(Piperidin-4-Yl)Pyridine Dihydrochloride
CAS No.	1260821-66-6
Molecular Formula	C10H14Cl2FN2
Molecular Weight	261.14 g/mol
Synonyms	4-(3-Fluoropyridin-4-yl)piperidine dihydrochloride; 3-Fluoro-4-(4-piperidinyl)pyridine dihydrochloride; 4-(3-Fluoro-4-pyridinyl)piperidine dihydrochloride; 3-Fluoro-4-piperidin-4-ylpyridine dihydrochloride; 1260821-66-6; 4-(3-Fluoropyridin-4-yl)piperidine hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Piperidin-4-Yl)Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.