Description

5-(Boc-Amino)Pyridine-2-Ethanol is a high-purity, protected amino alcohol building block of significant importance in modern organic synthesis. Its value lies in the orthogonal protection of the amine group by the tert-butoxycarbonyl (Boc) moiety, which is stable under a wide range of reaction conditions yet readily cleaved under mild acidic conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Peptidomimetic Synthesis: Used to introduce functionalized pyridine-ethanol side chains into peptide backbones to enhance bioavailability and binding affinity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the creation of new active ingredients for crop protection products.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules due to its reactive alcohol and protected amine functionalities.
• Material Science: Can be incorporated into polymers and functional materials to impart specific chemical properties.

Basic Information

Product Name	5-(Boc-Amino)Pyridine-2-Ethanol
CAS No.	1260802-13-8
Molecular Formula	C12H18N2O3
Molecular Weight	238.28 g/mol
Synonyms	2-(5-((tert-Butoxycarbonyl)amino)pyridin-2-yl)ethanol; 5-((tert-Butoxycarbonyl)amino)-2-pyridineethanol; 2-(5-(Boc-amino)pyridin-2-yl)ethanol; 5-(N-Boc-amino)-2-pyridineethanol; 5-(tert-Butoxycarbonylamino)-2-pyridineethanol; 5-(Boc-NH)-2-PyEtOH; Boc-5-Amino-2-pyridineethanol; 1260802-13-8
EINECS	Contact for details

Quality Control

Our 5-(Boc-Amino)Pyridine-2-Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and cGMP manufacturing. Certificates of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.