Description

(2-Amino-4,6-Difluorophenyl)Methanol is a versatile fluorinated aromatic building block with a bifunctional amino and alcohol group. This compound is critical for the synthesis of complex molecules where precise molecular architecture and fluorination are required. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and pesticides with enhanced activity and environmental profile.
• Ligand and Catalyst Development: Used to create specialized chelating ligands for metal-catalyzed cross-coupling reactions in fine chemical manufacturing.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and specialty materials.
• Fluorine Chemistry Research: Essential compound for academic and industrial research exploring the effects of fluorine substitution on biological activity and material properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	(2-Amino-4,6-Difluorophenyl)Methanol
CAS No.	1260783-44-5
Molecular Formula	C7H7F2NO
Molecular Weight	159.13 g/mol
Synonyms	2-Amino-4,6-difluorobenzyl alcohol; (2-Amino-4,6-difluorophenyl)methanol; 4,6-Difluoro-2-aminobenzyl alcohol; 2-(Aminomethyl)-3,5-difluorophenol; Benzenemethanol, 2-amino-4,6-difluoro-; 2-Amino-α,4,6-trifluorotoluene (reduction product context); 4,6-Difluoroanthranilyl alcohol
EINECS	Contact for details

Quality Control

Every batch of (2-Amino-4,6-Difluorophenyl)Methanol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and IR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.