Description

Benzyl 4-((tert-Butoxycarbonyl(Methyl)Amino)Methyl)Piperidine-1-Carboxylate CAS NO 1260763-75-4 is a high-purity, protected piperidine derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially within therapeutic areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to introduce and protect specific amine functionalities.
• Peptidomimetic Synthesis: Serves as a constrained scaffold to mimic peptide secondary structures, enhancing metabolic stability and bioavailability in drug design.
• Chemical Biology Probes: Employed in the development of tool compounds and molecular probes for studying biological pathways and enzyme functions.
• Process Chemistry Development: Utilized in route scouting and scale-up processes for the commercial manufacturing of complex active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis organizations (CSOs) and CDMOs producing specialized fine chemicals for clients.

Basic Information

Item	Detail
Product Name	Benzyl 4-((tert-Butoxycarbonyl(Methyl)Amino)Methyl)Piperidine-1-Carboxylate
CAS No.	1260763-75-4
Molecular Formula	C20H30N2O4
Molecular Weight	362.47 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-4-[[[tert-butoxycarbonyl(methyl)amino]methyl]piperidine; 4-[[(tert-Butoxycarbonyl)(methyl)amino]methyl]-1-(benzyloxycarbonyl)piperidine; 1-CBz-4-((Boc-N-Me-amino)methyl)piperidine; N-Boc-N-methyl-1-CBz-4-piperidinemethylamine; Benzyl 4-[(N-Boc-N-methylamino)methyl]piperidine-1-carboxylate; 1-CBz-4-[(N-Boc-N-Me)aminomethyl]piperidine; Piperidine-1-carboxylic acid, 4-[[[(1,1-dimethylethoxy)carbonyl](methyl)amino]methyl]-, phenylmethyl ester
EINECS	Contact for details

Quality Control

Our Benzyl 4-((tert-Butoxycarbonyl(Methyl)Amino)Methyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 97.0%
Purity (HPLC Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.