Description

6-Chloro-3-Iodo-1H-Pyrazolo[4,3-C]Pyridine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its unique halogenated pyrazolopyridine scaffold, which provides versatile reactivity for constructing complex molecular architectures. Pharmaceutical and agrochemical researchers need it as a critical intermediate in the development of novel active ingredients, particularly for targeted therapies and crop protection agents. Its specific substitution pattern makes it a sought-after precursor for Suzuki-Miyaura and other cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, anticancer agents, and other small-molecule drug candidates.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology: Employed as a molecular probe or tag in bioconjugation and proteomics research due to its reactive halogen sites.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for palladium-catalyzed Suzuki, Sonogashira, and Buchwald-Hartwig reactions.
• Library Synthesis: A versatile scaffold for generating diverse compound libraries in high-throughput screening for drug discovery.

Basic Information

Item	Detail
Product Name	6-Chloro-3-Iodo-1H-Pyrazolo[4,3-C]Pyridine
CAS No.	1260672-72-7
Molecular Formula	C6H3ClIN3
Molecular Weight	279.47 g/mol
Synonyms	6-Chloro-3-iodo-1H-pyrazolo[4,3-c]pyridine; 1H-Pyrazolo[4,3-c]pyridine, 6-chloro-3-iodo-; 3-Iodo-6-chloro-1H-pyrazolo[4,3-c]pyridine; 6-Chloro-3-iodopyrazolo[4,3-c]pyridine; Pyrazolo[4,3-c]pyridine, 6-chloro-3-iodo-1H-; CAS 1260672-72-7
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Iodo-1H-Pyrazolo[4,3-C]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.