Description

6-Chloro-3-Fluoropyridin-2-Amine is a high-purity fluorinated pyridine derivative, a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific halogen substitution pattern enables precise molecular modifications. It is primarily needed by research and development chemists, process scale-up teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine and chlorine functionalities into complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for functionalized ligands and monomers used in catalysis and polymer chemistry.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and developing novel synthetic methodologies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	6-Chloro-3-Fluoropyridin-2-Amine
CAS No.	1260672-14-7
Molecular Formula	C5H4ClFN2
Molecular Weight	146.55 g/mol
Synonyms	2-Amino-6-chloro-3-fluoropyridine; 3-Fluoro-6-chloropyridin-2-amine; 6-Chloro-3-fluoro-2-pyridinamine; 2-Pyridinamine, 6-chloro-3-fluoro-; 6-Chloro-3-fluoropyridin-2-ylamine; 6-Chloro-3-fluoro-2-aminopyridine; 2-Amino-3-fluoro-6-chloropyridine
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Fluoropyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.