Description

5-Bromo-4-Fluoro-2-Iodopyridine is a highly functionalized pyridine derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought after by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its halogenated structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The iodine and bromine substituents make it an excellent substrate for sequential Suzuki, Stille, and Sonogashira couplings to build complex biaryl systems.

Basic Information

Product Name	5-Bromo-4-Fluoro-2-Iodopyridine
CAS No.	1260669-95-1
Molecular Formula	C5H2BrFIN
Molecular Weight	301.88 g/mol
Synonyms	2-Iodo-5-bromo-4-fluoropyridine; 4-Fluoro-5-bromo-2-iodopyridine; 5-Bromo-4-fluoro-2-iodopyridine; Pyridine, 5-bromo-4-fluoro-2-iodo-; 1260669-95-1; 2-Iodo-4-fluoro-5-bromopyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Fluoro-2-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC & NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.