Description

Methyl 6-Amino-4-Bromonicotinate CAS NO 1260667-30-8 is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs. Pharmaceutical, agrochemical, and fine chemical manufacturers rely on this brominated nicotinate ester for its precise reactivity in cross-coupling and functional group transformations.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Building block for developing new crop protection agents and herbicides.
• Material Science: Used in the creation of functionalized ligands for catalysis and advanced polymeric materials.
• Chemical Synthesis: Versatile reagent for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Academic & R&D: Essential compound for exploratory research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	Methyl 6-Amino-4-Bromonicotinate
CAS No.	1260667-30-8
Molecular Formula	C7H7BrN2O2
Molecular Weight	231.05 g/mol
Synonyms	4-Bromo-6-aminonicotinic acid methyl ester; Methyl 4-bromo-6-aminopyridine-3-carboxylate; 6-Amino-4-bromonicotinic acid methyl ester; 3-Pyridinecarboxylic acid, 6-amino-4-bromo-, methyl ester; Methyl 6-amino-4-bromo-3-pyridinecarboxylate; 4-Bromo-6-amino-3-pyridinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 6-Amino-4-Bromonicotinate is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles via HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); therefore, containers must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.