Description

2-Bromo-4-(2-Pyrrolidinyl)Pyridine is a high-value brominated heterocyclic building block featuring a pyridine core substituted with a pyrrolidine moiety. This compound is essential for medicinal chemistry research and pharmaceutical development, serving as a key precursor for the synthesis of complex bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile chemical handle.
• Agrochemical Research: Serves as a precursor in the development of novel active ingredients for crop protection.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology: Used as a molecular probe or tag in biochemical and cellular studies.
• Academic Research: A valuable reagent for synthetic organic chemistry and methodology development in university and institutional labs.

Basic Information

Product Name	2-Bromo-4-(2-Pyrrolidinyl)Pyridine
CAS No.	1260665-46-0
Molecular Formula	C9H11BrN2
Molecular Weight	227.10 g/mol
Synonyms	4-(Pyrrolidin-2-yl)-2-bromopyridine; 2-Bromo-4-(2-pyrrolidinyl)pyridine; 2-Bromo-4-(pyrrolidin-2-yl)pyridine; 2-Bromo-4-(2-pyrrolidyl)pyridine; Pyridine, 2-bromo-4-(2-pyrrolidinyl)-; 1260665-46-0
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(2-Pyrrolidinyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.