Description

1-(2-Chloropyridin-4-Yl)Cyclobutanamine is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclobutane-pyridine hybrid structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and oncological targets.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting protein kinases and other enzymes.
• Agrochemical Research: Serves as a structural motif in the development of new-generation herbicides and pesticides with enhanced efficacy.
• Ligand Synthesis: Used in medicinal chemistry for constructing sophisticated ligands in catalyst systems and receptor-binding studies.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with specific electronic or mechanical properties.

Basic Information

Product Name	1-(2-Chloropyridin-4-Yl)Cyclobutanamine
CAS No.	1260664-27-4
Molecular Formula	C9H11ClN2
Molecular Weight	182.65 g/mol
Synonyms	1-(2-Chloro-4-pyridinyl)cyclobutanamine; Cyclobutanamine, 1-(2-chloro-4-pyridinyl)-; 4-(1-Aminocyclobutyl)-2-chloropyridine; 2-Chloro-4-(1-aminocyclobutyl)pyridine; 1-(2-Chloropyridin-4-yl)cyclobutan-1-amine; 1260664-27-4; 1-(2-Chloro-pyridin-4-yl)-cyclobutanamine
EINECS	Contact for details

Quality Control

Our 1-(2-Chloropyridin-4-Yl)Cyclobutanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for sensitive R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.