Description

6-Amino-5-Hydroxy-3-Pyridinecarboxylic Acid Methyl Ester is a high-purity, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both amino and hydroxy substituents on the pyridine ring, makes it a versatile intermediate for constructing complex molecules with specific pharmacological or material science properties. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of functional organic materials, such as metal-organic frameworks (MOFs) or organic semiconductors.
• Bioconjugation Chemistry: The reactive ester and amino groups facilitate its use in linking biomolecules for diagnostic or therapeutic applications.
• Academic & Contract Research: Essential reagent for methodological studies in heterocyclic and medicinal chemistry within university and CRO laboratories.

Basic Information

Product Name	6-Amino-5-Hydroxy-3-Pyridinecarboxylic Acid Methyl Ester
CAS No.	1260663-92-0
Molecular Formula	C8H10N2O3
Molecular Weight	182.18 g/mol
Synonyms	Methyl 6-amino-5-hydroxy-3-pyridinecarboxylate; 5-Hydroxy-6-aminonicotinic acid methyl ester; 3-Pyridinecarboxylic acid, 6-amino-5-hydroxy-, methyl ester; Methyl 5-hydroxy-6-aminonicotinate; 6-Amino-5-hydroxynicotinic acid methyl ester; Methyl 6-amino-5-hydroxynicotinate
EINECS	Contact for details

Quality Control

Our 6-Amino-5-Hydroxy-3-Pyridinecarboxylic Acid Methyl Ester is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.