Description

6-tert-Butyl 3-Methyl 4,5-Dihydroisoxazolo[5,4-C]Pyridine-3,6(7H)-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1260655-07-9. This compound is a critical building block in modern organic synthesis, valued for its complex fused heterocyclic structure that serves as a key precursor in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the discovery and synthesis of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

This specialized intermediate is designed for high-value synthetic applications. Its primary uses include:

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates and novel bioactive molecules.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.
• Academic Research: Employed in university and institutional labs for methodological development and the study of heterocyclic chemistry.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	6-tert-Butyl 3-Methyl 4,5-Dihydroisoxazolo[5,4-C]Pyridine-3,6(7H)-Dicarboxylate
CAS No.	1260655-07-9
Molecular Formula	C15H20N2O5
Molecular Weight	308.33 g/mol
Synonyms	6-tert-Butyl 3-methyl 4,7-dihydroisoxazolo[5,4-c]pyridine-3,6(5H)-dicarboxylate; tert-Butyl 3-methyl 4,7-dihydroisoxazolo[5,4-c]pyridine-3,6(5H)-dicarboxylate; 3,6(7H)-Dicarboxylic acid, 4,5-dihydroisoxazolo[5,4-c]pyridine-, 6-(1,1-dimethylethyl) 3-methyl ester; Isoxazolopyridine dicarboxylate derivative; BOC-protected isoxazolopyridine intermediate; 1260655-07-9; Fused isoxazole-pyridine intermediate
EINECS	Contact for details

Quality Control

Our production of 6-tert-Butyl 3-Methyl 4,5-Dihydroisoxazolo[5,4-C]Pyridine-3,6(7H)-Dicarboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. Our quality system is designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediates, ensuring traceability and reliability for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.