Description

Pyridin-4-Yl-Glycine tert-Butyl Ester Dihydrochloride is a high-purity, protected amino acid derivative essential for advanced pharmaceutical research and development. This compound serves as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry for drug discovery programs. It is primarily utilized by research scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Chemistry: Used as a protected glycine analog for the solid-phase and solution-phase synthesis of modified peptides and peptidomimetics.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Chemical Biology Probes: Acts as a precursor for developing labeled compounds and molecular probes to study biological pathways.
• Process Development: Serves as a starting material for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Academics & R&D: Utilized in university and institutional research for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	Pyridin-4-Yl-Glycine tert-Butyl Ester Dihydrochloride
CAS No.	1260638-12-7
Molecular Formula	C11H17Cl2N2O2
Molecular Weight	280.17 g/mol
Synonyms	4-Pyridylglycine tert-butyl ester dihydrochloride; tert-Butyl 2-amino-2-(pyridin-4-yl)acetate dihydrochloride; 2-Amino-2-(4-pyridinyl)acetic acid 1,1-dimethylethyl ester dihydrochloride; Glycine, N-(4-pyridinyl)-, 1,1-dimethylethyl ester, dihydrochloride; (4-Pyridyl)glycine tert-butyl ester hydrochloride; Pyridin-4-ylglycine O-tert-butyl ester dihydrochloride
EINECS	Contact for details

Quality Control

Our Pyridin-4-Yl-Glycine tert-Butyl Ester Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.