Description

Pyridin-2-Yl-Glycine tert-Butyl Ester is a specialized, high-purity chemical building block designed for advanced synthetic applications. This compound is valued for its role as a protected amino acid derivative, offering a versatile handle for constructing complex molecules in a controlled manner. It is primarily utilized by research institutions and pharmaceutical development teams engaged in the synthesis of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals. Its specific structure makes it a critical intermediate for medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Peptidomimetic Research: Used to incorporate modified amino acid structures into peptide chains to enhance stability, bioavailability, or biological activity.
• Chemical Biology Probes: Serves as a precursor for creating labeled or tagged molecules used to study biological pathways and protein interactions.
• Agrochemical Synthesis: Employed in the research and development of advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Utilized in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, complex heterocyclic intermediates.

Basic Information

Product Name	Pyridin-2-Yl-Glycine tert-Butyl Ester
CAS No.	1260637-94-2
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	2-Pyridylglycine tert-butyl ester; tert-Butyl 2-(pyridin-2-yl)glycinate; Glycine, N-2-pyridinyl-, 1,1-dimethylethyl ester; (2-Pyridylamino)acetic acid tert-butyl ester; N-(Pyridin-2-yl)glycine tert-butyl ester; Boc-Pyridin-2-Yl-Glycine-OH (common misnomer); 1260637-94-2; Py-2-Gly-OtBu
EINECS	Contact for details

Quality Control

Every batch of Pyridin-2-Yl-Glycine tert-Butyl Ester is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request. We support development projects requiring compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is stable under inert atmosphere but may degrade upon prolonged exposure to strong acids or organic solvents. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.