Description

5-Amino-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylic Acid is a high-value, nitrogen-rich heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of complex molecules, enabling the development of novel active ingredients. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing advanced pyrazolopyridine scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small-molecule therapeutics targeting various diseases.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology & Probe Development: Serves as a versatile scaffold for creating molecular probes and tools to study biological pathways and enzyme functions.
• Material Science Research: Investigated as a building block for advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or functional polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and library production for client projects.

Basic Information

Product Name	5-Amino-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylic Acid
CAS No.	1260387-14-1
Molecular Formula	C7H6N4O2
Molecular Weight	178.15 g/mol
Synonyms	5-Amino-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid; 3-Carboxy-5-amino-1H-pyrazolo[3,4-b]pyridine; 5-Amino-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-3-carboxylic acid, 5-amino-; 5-Amino-1H-1,2,3-triazolo[4,5-b]pyridine-3-carboxylic acid (tautomeric form); 5-Aminopyrazolo[3,4-b]pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Amino-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.