Description

5-Amino-7-azaindole-2-carboxylic acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceutical agents and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A critical scaffold for synthesizing kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Chemical Biology & Proteomics: Serves as a versatile building block for creating chemical probes, fluorescent tags, and activity-based protein profiling (ABPP) reagents.
• Material Science: Potential precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers, due to its fused heterocyclic structure.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in heterocyclic and medicinal chemistry.
• Custom Synthesis & Scale-up: A starting material for the contract manufacturing of proprietary compounds and active pharmaceutical ingredients (APIs) at various scales.

Basic Information

Product Name	5-Amino-7-azaindole-2-carboxylic acid
CAS No.	1260385-74-7
Molecular Formula	C8H7N3O2
Molecular Weight	177.16 g/mol
Synonyms	5-Amino-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 5-Amino-7-azaindole-2-carboxylic acid; 2-Carboxy-5-amino-7-azaindole; 5-Amino-2-carboxy-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-amino-; 5-Amino-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Amino-7-azaindole-2-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.