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2-Amino-9-[(2,3,5-Tri-o-Benzoyl-β-D-Ribofuranosyl)]-9H-Purine CAS NO 1260177-41-0


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CAS No.:1260177-41-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Amino-9-[(2,3,5-Tri-o-Benzoyl-β-D-Ribofuranosyl)]-9H-Purine is a key nucleoside derivative and a crucial protected intermediate in synthetic organic chemistry. This compound matters for its role as a building block in the synthesis of modified nucleosides and nucleotides, enabling precise control over molecular structure. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of antiviral agents, oligonucleotide therapeutics, and other advanced biomolecules.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
  • Oligonucleotide Synthesis: Serves as a protected monomer for the solid-phase synthesis of modified DNA and RNA strands for research and therapeutic applications.
  • Biochemical Research: Used in studies exploring enzyme mechanisms, nucleic acid interactions, and the development of diagnostic probes.
  • Prodrug Development: Employed in creating prodrug forms of nucleoside analogs to improve bioavailability and targeting.
  • Antisense Technology: A building block for antisense oligonucleotides designed to modulate gene expression.
  • Chemical Biology Tool: Utilized to label or modify nucleic acids to investigate biological processes at the molecular level.

Basic Information

Product Name 2-Amino-9-[(2,3,5-Tri-o-Benzoyl-β-D-Ribofuranosyl)]-9H-Purine
CAS No. 1260177-41-0
Molecular Formula C33H27N5O7
Molecular Weight 605.60 g/mol
Synonyms 2-Amino-9-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-9H-purine; 2-Aminoadenosine 2',3',5'-tribenzoate; 2-Amino-9-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine; N2-Amino-2',3',5'-tri-O-benzoyladenosine; Tribenzoyl-2-aminoadenosine; 2-NH2-Adenosine tribenzoate; Protected 2-Aminoadenosine
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Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide high-purity material suitable for research and pharmaceutical synthesis, supported by comprehensive analytical data. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Single Unknown Impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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