Description

3-Bromo-2-(4-Trifluoromethylphenyl)Pyridine is a high-value brominated pyridine derivative featuring a trifluoromethylphenyl substituent, making it a versatile and critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique halogenated and fluorinated structure enables precise modulation of biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and as a halogenated scaffold for further functionalization in medicinal chemistry programs.
• Life Science Reagents: Utilized in the preparation of biochemical probes, fluorescent tags, and other research tools for biological studies.

Basic Information

Product Name	3-Bromo-2-(4-Trifluoromethylphenyl)Pyridine
CAS No.	1259091-98-9
Molecular Formula	C12H7BrF3N
Molecular Weight	302.09 g/mol
Synonyms	3-Bromo-2-[4-(trifluoromethyl)phenyl]pyridine; 2-(4-Trifluoromethylphenyl)-3-bromopyridine; 3-Bromo-2-(4-trifluoromethylphenyl)pyridine; 1259091-98-9; 3-Bromo-2-(α,α,α-trifluoro-p-tolyl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-(4-Trifluoromethylphenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.