Description

4-[3-(Trifluoromethyl)-3H-Diazirin-3-Yl]Benzenemethanamine Hydrochloride is a specialized, high-value chemical building block featuring a photoreactive diazirine group and a benzylamine hydrochloride moiety. This compound is critically important for advanced research and development, enabling the study of biomolecular interactions and protein structures through photoaffinity labeling and cross-linking techniques. It is primarily utilized by pharmaceutical researchers, chemical biologists, and academic institutions engaged in proteomics, drug discovery, and the development of novel biochemical probes.

Application

• Photoaffinity Labeling Probes: A key reagent for synthesizing probes to covalently capture and identify transient or weak protein-ligand interactions upon UV light activation.
• Chemical Biology Research: Used in the study of protein function, structure, and interaction networks within complex biological systems.
• Proteomics and Target Identification: Essential for identifying unknown biological targets of drug candidates or bioactive small molecules in live cells.
• Bioconjugation and Linker Chemistry: Serves as a versatile intermediate for attaching photoreactive groups to other molecules, antibodies, or surfaces.
• Material Science Functionalization: Employed to introduce photoreactive amine functionalities onto polymers or surfaces for advanced material applications.
• Academic and Industrial R&D: A fundamental tool in laboratories focused on pioneering new methodologies in biochemistry and medicinal chemistry.

Basic Information

Product Name	4-[3-(Trifluoromethyl)-3H-Diazirin-3-Yl]Benzenemethanamine Hydrochloride
CAS No.	1258874-29-1
Molecular Formula	C9H7ClF3N3
Molecular Weight	249.62 g/mol
Synonyms	4-(3-(Trifluoromethyl)diazirin-3-yl)benzylamine hydrochloride; 3-[4-(Aminomethyl)phenyl]-3-(trifluoromethyl)-3H-diazirine hydrochloride; Benzylamine, 4-[3-(trifluoromethyl)-3H-diazirin-3-yl]-, hydrochloride; Trifluoromethylphenyl Diazirine Benzylamine HCl; Photoaffinity Labeling Amine Reagent; TPD-Benzylamine HCl; Diazirine-Benzylamine Crosslinker
EINECS	Contact for details

Quality Control

Every batch of 4-[3-(Trifluoromethyl)-3H-Diazirin-3-Yl]Benzenemethanamine Hydrochloride is manufactured and analyzed under strict quality management protocols to ensure the high purity and consistency required for sensitive research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting industry standards. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.