Description

Ethyl 6-Bromo-1,4-Dihydro-7-Methyl-4-Oxoquinoline-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the quinolone carboxylic acid ester class. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of antibacterial agents. It is essential for research institutions and manufacturers engaged in the production of next-generation quinolone-based therapeutics, offering a reliable and scalable route for complex molecular construction.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent antibacterial fluoroquinolone and quinolone APIs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new antimicrobial agents.
• Chemical Synthesis: Serves as a versatile building block for introducing the bromo-substituted quinoline core into more complex molecular architectures.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	Ethyl 6-Bromo-1,4-Dihydro-7-Methyl-4-Oxoquinoline-3-Carboxylate
CAS No.	1258652-59-3
Molecular Formula	C₁₃H₁₂BrNO₃
Molecular Weight	310.15 g/mol
Synonyms	Ethyl 6-bromo-7-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate; 6-Bromo-7-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester; 1,4-Dihydro-6-bromo-7-methyl-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 1,4-dihydro-6-bromo-7-methyl-4-oxo-, ethyl ester; 6-Bromo-7-methyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromo-1,4-Dihydro-7-Methyl-4-Oxoquinoline-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.